Scientific Program

11 June 2019
9:00 to 9:30	Registration and Reception
09:30 to 10:10	Keynote lecture Eugene Shakhnovich, Harvard University, USA Disulfide exchange and self-catalyzed aggregation in cataract-associated human γD crystallin: “hot potato”, “interface stealing” and all that
10:10 to 10:25	Selected talk Mai Suan Li, Polish Academy of Sciences, Poland Multi-scale molecular dynamics simulation of amyloid beta oligomers
10:25 to 10:40	Selected talk Velia Minicozzi, University of Rome Tor Vergata, Italy Monitoring insulin aggregated structures in the presence of epigallocatechin-3 gallate and melatonin by molecular dynamics simulations
10:40 to 10:55	Selected talk Guilherme Moreira, University of Lisbon, Portugal Zinc binding to Tau influences aggregation kinetics and oligomer distribution
10:55 to 11:10	Selected talk Ricardo Pires, University of Minho, Portugal Vescalagin/castalagin reduces Aβ42 cytotoxicity through the modulation of its aggregation pathway
11:10 to 11:25	Selected talk Alexander Buell, Technical University of Denmark, Denmark The autocatalytic secondary nucleation of amyloid fibrils
11:25 to 11:50	Coffee break Poster session
11:50 to 12:30	Keynote lecture Ehud Gazit, Tel Aviv University, Israel The extended amyloid hypothesis: Fibril formation by proteins, peptides, metabolites and cross-seeding assemblies
12:30 to 13:10	Keynote lecture Cláudio Gomes, University of Lisbon, Portugal Alzheimer’s disease: protein aggregation in the brain and new inflammatory chaperones at the rescue
13:10 to 14:30	Lunch break
14:30 to 15:10	Keynote lecture Sophie Jackson, University of Cambridge, UK Why are there knots in proteins?
15:10 to 15:40	Invited talk Raffaello Potestio, Univerity of Trento, Italy Searching the optimal folding routes of a complex lasso protein
15:40 to 16:10	Invited talk Miguel Machuqueiro, Universidade de Lisbon, Portugal The impact of pH on protein/protein and protein/membrane interactions
16:10 to 16:40	Coffee break Poster session
16:40 to 17:20	Keynote lecture Marek Cieplak, Institute of Physics, Poland Emergence of knots in intrinsically disordered proteins
17:20 to 17:35	Selected talk João Especial, University of Lisbon, Portugal Hydrophobic confinement modulates thermal stability and assists knotting in the folding of tangled proteins
17:35 to 17:50	Selected talk Diogo Vila-Viçosa, University of Lisbon, Portugal Folding of cyclic peptides stabilized by halogen bonds
17:50 to 18:05	Selected talk Isha Malhotra, Indian Institute of Technology, India Phase diagram of two-patch colloidal particles under competing isotropic and anisotropic interactions

 

12 June 2019
9:30 to 10:10	Keynote lecture Kresten Lindorff-Larsen, University of Copenhagen, Denmark From protein folding to predictions of pathogenic protein variants
10:10 to 10:25	Selected talk Rodrigo Maillard, Georgetown University, USA Activation of a Protein Kinase Via Asymmetric Allosteric Coupling of Structurally Conserved Signaling Modules
10:25 to 10:40	Selected talk Ana Melo, University of Lisbon, Portugal Exploring the conformational plasticity of tau at the single-molecule level
10:40 to 10:55	Selected talk Miguel Soler, Istituto Italiano di Tecnologia, Italy In silico design of protein binders for medical applications
10:55 to 11:10	Selected talk João Carlos Marcos, University of Minho, Portugal Inhibition of protein aggregation by poly(ethylene glycol)
11:10 to 11:40	Coffee break Poster session Group photo
11:40 to 12:20	Keynote lecture Dave Thirumalai, University of Austin Texas, USA Role of Water in Protein Aggregation and Amyloid Polymorphism
12:20 to 13:00	Keynote lecture Margarida Amaral, University of Lisbon, Portugal Impact of CFTR In Vivo Folding and Misfolding for Cystic Fibrosis
13:00 to 14:30	Lunch break
14:30 to 15:10	Keynote lecture Rita Horváth, University of Cambridge, UK What causes tissue specific phenotypes in mitochondrial disease?
15:10 to 15:40	Invited talk Paula Leandro, University of Lisbon, Portugal Advances and Challenges in the Treatment of Inborn Error of Metabolism: Small Molecules and Protein Misfolding
15:40 to 15:55	Selected talk Carlos Farinha, University of Lisbon, Portugal Exploring the Endoplasmic Reticulum Quality Control for CFTR
15:55 to 16:10	Selected talk Joana Ribeiro, University of Lisbon, Portugal Structural and Functional Effects of Missense Mutations on Glutaryl-CoA Dehydrogenase
16:10 to 16:50	Keynote lecture Bill Eaton, National Institutes of Health, USA Using physical chemistry to screen for a drug to treat sickle cell disease

 

There may be changes to the program until the event.