11 June 2019
9:00 to 9:30 Registration and Reception
09:30 to 10:10 Keynote lecture
Eugene Shakhnovich, Harvard University, USA
Disulfide exchange and self-catalyzed aggregation in cataract-associated human γD crystallin: “hot potato”, “interface stealing” and all that
10:10 to 10:25 Selected talk
Mai Suan Li, Polish Academy of Sciences, Poland
Multi-scale molecular dynamics simulation of amyloid beta oligomers
10:25 to 10:40 Selected talk
Velia Minicozzi, University of Rome Tor Vergata, Italy
Monitoring insulin aggregated structures in the presence of epigallocatechin-3 gallate and melatonin by molecular dynamics simulations
10:40 to 10:55 Selected talk
Guilherme Moreira, University of Lisbon, Portugal
Zinc binding to Tau influences aggregation kinetics and oligomer distribution
10:55 to 11:10 Selected talk
Ricardo Pires, University of Minho, Portugal
Vescalagin/castalagin reduces Aβ42 cytotoxicity through the modulation of its aggregation pathway
11:10 to 11:25 Selected talk
Alexander Buell, Technical University of Denmark, Denmark
The autocatalytic secondary nucleation of amyloid fibrils
11:25 to 11:50 Coffee break
Poster session
11:50 to 12:30 Keynote lecture
Ehud Gazit, Tel Aviv University, Israel
The extended amyloid hypothesis: Fibril formation by proteins, peptides, metabolites and cross-seeding assemblies
12:30 to 13:10 Keynote lecture
Cláudio Gomes, University of Lisbon, Portugal
Alzheimer’s disease: protein aggregation in the brain and new inflammatory chaperones at the rescue
13:10 to 14:30 Lunch break
14:30 to 15:10 Keynote lecture
Sophie Jackson, University of Cambridge, UK
Why are there knots in proteins?
15:10 to 15:40 Invited talk
Raffaello Potestio, Univerity of Trento, Italy
Searching the optimal folding routes of a complex lasso protein
15:40 to 16:10 Invited talk
Miguel Machuqueiro, Universidade de Lisbon, Portugal
The impact of pH on protein/protein and protein/membrane interactions
16:10 to 16:40 Coffee break
Poster session
16:40 to 17:20 Keynote lecture
Marek Cieplak, Institute of Physics, Poland
Emergence of knots in intrinsically disordered proteins
17:20 to 17:35 Selected talk
João Especial, University of Lisbon, Portugal
Hydrophobic confinement modulates thermal stability and assists knotting in the folding of tangled proteins
17:35 to 17:50 Selected talk
Diogo Vila-Viçosa, University of Lisbon, Portugal
Folding of cyclic peptides stabilized by halogen bonds
17:50 to 18:05 Selected talk
Isha Malhotra, Indian Institute of Technology, India
Phase diagram of two-patch colloidal particles under competing isotropic and anisotropic interactions


12 June 2019
9:30 to 10:10 Keynote lecture
Kresten Lindorff-Larsen, University of Copenhagen, Denmark
From protein folding to predictions of pathogenic protein variants
10:10 to 10:25 Selected talk
Rodrigo Maillard, Georgetown University, USA
Activation of a Protein Kinase Via Asymmetric Allosteric Coupling of Structurally Conserved Signaling Modules
10:25 to 10:40 Selected talk
Ana Melo, University of Lisbon, Portugal
Exploring the conformational plasticity of tau at the single-molecule level
10:40 to 10:55 Selected talk
Miguel Soler, Istituto Italiano di Tecnologia, Italy
In silico design of protein binders for medical applications
10:55 to 11:10 Selected talk
João Carlos Marcos, University of Minho, Portugal
Inhibition of protein aggregation by poly(ethylene glycol)
11:10 to 11:40 Coffee break
Poster session
Group photo
11:40 to 12:20 Keynote lecture
Dave Thirumalai, University of Austin Texas, USA
Role of Water in Protein Aggregation and Amyloid Polymorphism
12:20 to 13:00 Keynote lecture
Margarida Amaral, University of Lisbon, Portugal
Impact of CFTR In Vivo Folding and Misfolding for Cystic Fibrosis
13:00 to 14:30 Lunch break
14:30 to 15:10 Keynote lecture
Rita Horváth, University of Cambridge, UK
What causes tissue specific phenotypes in mitochondrial disease?
15:10 to 15:40 Invited talk
Paula Leandro, University of Lisbon, Portugal
Advances and Challenges in the Treatment of Inborn Error of Metabolism: Small Molecules and Protein Misfolding
15:40 to 15:55 Selected talk
Carlos Farinha, University of Lisbon, Portugal
Exploring the Endoplasmic Reticulum Quality Control for CFTR
15:55 to 16:10 Selected talk
Joana Ribeiro, University of Lisbon, Portugal
Structural and Functional Effects of Missense Mutations on Glutaryl-CoA Dehydrogenase
16:10 to 16:50 Keynote lecture
Bill Eaton, National Institutes of Health, USA
Using physical chemistry to screen for a drug to treat sickle cell disease


There may be changes to the program until the event.